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Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application

BACKGROUND: Erythromycin, a hydrophobic antibiotic used to treat infectious diseases, is now gaining attention because of its anti-inflammatory effects and ability to inhibit osteoclasts formation. The aim of this study was to explore a cyclodextrin-erythromycin (CD-EM) complex for sustained treatme...

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Detalles Bibliográficos
Autores principales: Song, Wei, Yu, Xiaowei, Wang, Sunxi, Blasier, Ralph, Markel, David C, Mao, Guangzhao, Shi, Tong, Ren, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252670/
https://www.ncbi.nlm.nih.gov/pubmed/22228990
http://dx.doi.org/10.2147/IJN.S23530