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Supramolecular micellar nanoaggregates based on a novel chitosan/vitamin E succinate copolymer for paclitaxel selective delivery

BACKGROUND: Nowadays, many cytotoxic anticancer drugs exhibit low solubility and poor tumor selectivity, which means that the drug formulation is very important. For example, in the case of paclitaxel (PTX), Cremophor EL(®) (BASF, Ludwigshafen, Germany) needs to be used as a solubilizer in its clini...

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Detalles Bibliográficos
Autores principales: Lian, He, Sun, Jin, Yu, Yan Ping, Liu, Yan Hua, Cao, Wen, Wang, Yong Jun, Sun, Ying Hua, Wang, Si Ling, He, Zhong Gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252679/
https://www.ncbi.nlm.nih.gov/pubmed/22228999
http://dx.doi.org/10.2147/IJN.S26305