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Encapsulation of plasmid DNA in calcium phosphate nanoparticles: stem cell uptake and gene transfer efficiency

BACKGROUND: The purpose of this study was to develop calcium phosphate nanocomposite particles encapsulating plasmid DNA (CP-pDNA) nanoparticles as a nonviral vector for gene delivery. METHODS: CP-pDNA nanoparticles employing plasmid transforming growth factor beta 1 (TGF-β1) were prepared and chara...

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Detalles Bibliográficos
Autores principales: Cao, Xia, Deng, Wenwen, Wei, Yuan, Su, Weiyan, Yang, Yan, Wei, Yawei, Yu, Jiangnan, Xu, Ximing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252680/
https://www.ncbi.nlm.nih.gov/pubmed/22229000
http://dx.doi.org/10.2147/IJN.S27370