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The role of c-FLIP splice variants in urothelial tumours

Deregulation of apoptosis is common in cancer and is often caused by overexpression of anti-apoptotic proteins in tumour cells. One important regulator of apoptosis is the cellular FLICE-inhibitory protein (c-FLIP), which is overexpressed, for example, in melanoma and Hodgkin's lymphoma cells....

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Detalles Bibliográficos
Autores principales: Ewald, F, Ueffing, N, Brockmann, L, Hader, C, Telieps, T, Schuster, M, Schulz, W A, Schmitz, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252741/
https://www.ncbi.nlm.nih.gov/pubmed/22190004
http://dx.doi.org/10.1038/cddis.2011.131