Novel tumor suppressive function of Smad4 in serum starvation-induced cell death through PAK1–PUMA pathway

DPC4 (deleted in pancreatic cancer 4)/Smad4 is an essential factor in transforming growth factor (TGF)-β signaling and is also known as a frequently mutated tumor suppressor gene in human pancreatic and colon cancer. However, considering the fact that TGF-β can contribute to cancer progression throu...

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Detalles Bibliográficos
Autores principales: Lee, S-H, Jung, Y-S, Chung, J-Y, Oh, A Y, Lee, S-J, Choi, D H, Jang, S M, Jang, K-S, Paik, S S, Ha, N-C, Park, B-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252743/
https://www.ncbi.nlm.nih.gov/pubmed/22130069
http://dx.doi.org/10.1038/cddis.2011.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252743/
https://www.ncbi.nlm.nih.gov/pubmed/22130069
http://dx.doi.org/10.1038/cddis.2011.116

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