Cargando…
Tertiary alcohol preferred: Hydroxylation of trans-3-methyl-L-proline with proline hydroxylases
The enzymatic synthesis of tertiary alcohols by the stereospecific oxidation of tertiary alkyl centers is a most-straightforward but challenging approach, since these positions are sterically hindered. In contrast to P450-monooxygenases, there is little known about the potential of non-heme iron(II)...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252868/ https://www.ncbi.nlm.nih.gov/pubmed/22238542 http://dx.doi.org/10.3762/bjoc.7.193 |