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The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors

Herein we describe the application of a monolithic triphenylphosphine reagent to the Appel reaction in flow-chemistry processing, to generate various brominated products with high purity and in excellent yields, and with no requirement for further off-line purification.

Detalles Bibliográficos
Autores principales: Roper, Kimberley A, Lange, Heiko, Polyzos, Anastasios, Berry, Malcolm B, Baxendale, Ian R, Ley, Steven V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252869/
https://www.ncbi.nlm.nih.gov/pubmed/22238543
http://dx.doi.org/10.3762/bjoc.7.194