The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors

Herein we describe the application of a monolithic triphenylphosphine reagent to the Appel reaction in flow-chemistry processing, to generate various brominated products with high purity and in excellent yields, and with no requirement for further off-line purification.

Detalles Bibliográficos
Autores principales: Roper, Kimberley A, Lange, Heiko, Polyzos, Anastasios, Berry, Malcolm B, Baxendale, Ian R, Ley, Steven V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252869/
https://www.ncbi.nlm.nih.gov/pubmed/22238543
http://dx.doi.org/10.3762/bjoc.7.194
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author Roper, Kimberley A
Lange, Heiko
Polyzos, Anastasios
Berry, Malcolm B
Baxendale, Ian R
Ley, Steven V
author_facet Roper, Kimberley A
Lange, Heiko
Polyzos, Anastasios
Berry, Malcolm B
Baxendale, Ian R
Ley, Steven V
author_sort Roper, Kimberley A
collection PubMed
description Herein we describe the application of a monolithic triphenylphosphine reagent to the Appel reaction in flow-chemistry processing, to generate various brominated products with high purity and in excellent yields, and with no requirement for further off-line purification.
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spelling pubmed-32528692012-01-11 The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors Roper, Kimberley A Lange, Heiko Polyzos, Anastasios Berry, Malcolm B Baxendale, Ian R Ley, Steven V Beilstein J Org Chem Full Research Paper Herein we describe the application of a monolithic triphenylphosphine reagent to the Appel reaction in flow-chemistry processing, to generate various brominated products with high purity and in excellent yields, and with no requirement for further off-line purification. Beilstein-Institut 2011-12-08 /pmc/articles/PMC3252869/ /pubmed/22238543 http://dx.doi.org/10.3762/bjoc.7.194 Text en Copyright © 2011, Roper et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Roper, Kimberley A
Lange, Heiko
Polyzos, Anastasios
Berry, Malcolm B
Baxendale, Ian R
Ley, Steven V
The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors
title The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors
title_full The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors
title_fullStr The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors
title_full_unstemmed The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors
title_short The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors
title_sort application of a monolithic triphenylphosphine reagent for conducting appel reactions in flow microreactors
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252869/
https://www.ncbi.nlm.nih.gov/pubmed/22238543
http://dx.doi.org/10.3762/bjoc.7.194
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