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Investigating the influence of PFC transection and nicotine on dynamics of AMPA and NMDA receptors of VTA dopaminergic neurons

BACKGROUND: All drugs of abuse, including nicotine, activate the mesocorticolimbic system that plays critical roles in nicotine reward and reinforcement development and triggers glutamatergic synaptic plasticity on the dopamine (DA) neurons in the ventral tegmental area (VTA). The addictive behavior...

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Detalles Bibliográficos
Autores principales: Chen, Ting, Zhang, Die, Dragomir, Andrei, Kobayashi, Kunikazu, Akay, Yasemin, Akay, Metin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253050/
https://www.ncbi.nlm.nih.gov/pubmed/22018308
http://dx.doi.org/10.1186/1743-0003-8-58