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Transcriptional Regulation Is a Major Controller of Cell Cycle Transition Dynamics

DNA replication, mitosis and mitotic exit are critical transitions of the cell cycle which normally occur only once per cycle. A universal control mechanism was proposed for the regulation of mitotic entry in which Cdk helps its own activation through two positive feedback loops. Recent discoveries...

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Detalles Bibliográficos
Autores principales: Romanel, Alessandro, Jensen, Lars Juhl, Cardelli, Luca, Csikász-Nagy, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253096/
https://www.ncbi.nlm.nih.gov/pubmed/22238641
http://dx.doi.org/10.1371/journal.pone.0029716