Antiparallel EmrE exports drugs by exchanging between asymmetric structures

Small multidrug resistance (SMR) transporters provide an ideal system to study the minimal requirements for active transport. EmrE is an E. coli SMR transporter that exports a broad class of polyaromatic cation substrates, thus conferring resistance to drug compounds matching this chemical descripti...

Descripción completa

Detalles Bibliográficos
Autores principales: Morrison, Emma A., DeKoster, Gregory T., Dutta, Supratik, Clarkson, Michael W., Vafabakhsh, Reza, Bahl, Arjun, Kern, Dorothee, Ha, Taekjip, Henzler-Wildman, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253143/
https://www.ncbi.nlm.nih.gov/pubmed/22178925
http://dx.doi.org/10.1038/nature10703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253143/
https://www.ncbi.nlm.nih.gov/pubmed/22178925
http://dx.doi.org/10.1038/nature10703

Ejemplares similares