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NF-κB inducing kinase (NIK) modulates melanoma tumorigenesis by regulating expression of pro-survival factors through the β-catenin pathway

Nuclear factor-κB (NF-κB) inducing kinase (NIK) is a MAP3K that regulates the activation of NF-κB. NIK is often highly expressed in tumor cells, including melanoma, but the significance of this in melanoma progression has been unclear. Tissue microarray analysis of NIK expression reveals that dyspla...

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Detalles Bibliográficos
Autores principales: Thu, Yee Mon, Su, Yingjun, Yang, Jinming, Splittgerber, Ryan, Na, Songqing, Boyd, Alan, Mosse, Claudio, Simons, Christopher, Richmond, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253179/
https://www.ncbi.nlm.nih.gov/pubmed/21963849
http://dx.doi.org/10.1038/onc.2011.427