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MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia

Acute myeloblastic leukemia (AML) is characterized by the accumulation of abnormal myeloblasts (mainly granulocyte or monocyte precursors) in the bone marrow and blood. Though great progress has been made for improvement in clinical treatment during the past decades, only minority with AML achieve l...

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Detalles Bibliográficos
Autores principales: Zheng, Y-S, Zhang, H, Zhang, X-J, Feng, D-D, Luo, X-Q, Zeng, C-W, Lin, K-Y, Zhou, H, Qu, L-H, Zhang, P, Chen, Y-Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253429/
https://www.ncbi.nlm.nih.gov/pubmed/21643017
http://dx.doi.org/10.1038/onc.2011.208