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Developing and Activated T Cell Survival Depends on Differential Signaling Pathways to Regulate Anti-Apoptotic Bcl-x(L)

Survival of T cells in both the central and peripheral immune system determines its ultimate function in the regulation of immune responses. In the thymus, developing T cells undergo positive and negative selection to generate a T cell repertoire that responds to foreign, but not self, antigens. Dur...

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Detalles Bibliográficos
Autores principales: Wang, Ruiqing, Xie, Huimin, Huang, Zhaofeng, Shang, Weirong, Sun, Zuoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253460/
https://www.ncbi.nlm.nih.gov/pubmed/22235227
http://dx.doi.org/10.1155/2012/632837