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In Vivo Expression of Interleukin-37 Reduces Local and Systemic Inflammation in Concanavalin A-Induced Hepatitis

We recently reported that after LPS stimulation, IL-37 translocates to the nucleus and reduces the expression of proinflammatory cytokines. The aim of this study was to investigate whether transiently expressed IL-37 in mice reduces inflammation in concanavalin A (ConA)-induced hepatitis and LPS-ind...

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Detalles Bibliográficos
Autores principales: Bulau, Ana-Maria, Fink, Michaela, Maucksch, Christof, Kappler, Roland, Mayr, Doris, Wagner, Kai, Bufler, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253525/
https://www.ncbi.nlm.nih.gov/pubmed/22235179
http://dx.doi.org/10.1100/2011/968479