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Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors

Blockade of the renin-angiotensin system (RAS) is well recognized as an essential therapy in hypertensive, heart, and kidney diseases. There are several classes of drugs that block the RAS; these drugs are known to exhibit antifibrotic action. An analysis of the molecular mechanisms of action for th...

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Detalles Bibliográficos
Autores principales: Kanasaki, Megumi, Nagai, Takako, Kitada, Munehiro, Koya, Daisuke, Kanasaki, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253677/
https://www.ncbi.nlm.nih.gov/pubmed/22126210
http://dx.doi.org/10.1186/1755-1536-4-25