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The Effect of p38 Mitogen-Activated Protein Kinase Activation on Inflammatory Liver Damage following Hemorrhagic Shock in Rats

Hemorrhagic shock is a frequent cause of liver failure and often leads to a fatal outcome. Several studies have revealed that p38 MAPK is a key mediator in hemorrhagic damage of the primary organs through the activation of proinflammatory cytokines such as tumor necrosis factor (TNF)-α and interleuk...

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Detalles Bibliográficos
Autores principales: Sato, Hiroaki, Tanaka, Toshiko, Tanaka, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253806/
https://www.ncbi.nlm.nih.gov/pubmed/22253904
http://dx.doi.org/10.1371/journal.pone.0030124