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HIV-1 Promotes Renal Tubular Epithelial Cell Protein Synthesis: Role of mTOR Pathway

Tubular cell HIV-infection has been reported to manifest in the form of cellular hypertrophy and apoptosis. In the present study, we evaluated the role of mammalian target of rapamycin (mTOR) pathway in the HIV induction of tubular cell protein synthesis. Mouse proximal tubular epithelial cells (MPT...

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Detalles Bibliográficos
Autores principales: Rehman, Shabina, Husain, Mohammad, Yadav, Anju, Kasinath, Balakuntalam S., Malhotra, Ashwani, Singhal, Pravin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253808/
https://www.ncbi.nlm.nih.gov/pubmed/22253885
http://dx.doi.org/10.1371/journal.pone.0030071