Cargando…

HIV-1 Promotes Renal Tubular Epithelial Cell Protein Synthesis: Role of mTOR Pathway

Tubular cell HIV-infection has been reported to manifest in the form of cellular hypertrophy and apoptosis. In the present study, we evaluated the role of mammalian target of rapamycin (mTOR) pathway in the HIV induction of tubular cell protein synthesis. Mouse proximal tubular epithelial cells (MPT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rehman, Shabina, Husain, Mohammad, Yadav, Anju, Kasinath, Balakuntalam S., Malhotra, Ashwani, Singhal, Pravin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253808/ https://www.ncbi.nlm.nih.gov/pubmed/22253885 http://dx.doi.org/10.1371/journal.pone.0030071

Ejemplares similares

Oncoprotein DJ-1 interacts with mTOR complexes to effect transcription factor Hif1α-dependent expression of collagen I (α2) during renal fibrosis
por: Das, Falguni, et al.
Publicado: (2022)

Akt2 causes TGFβ-induced deptor downregulation facilitating mTOR to drive podocyte hypertrophy and matrix protein expression
por: Das, Falguni, et al.
Publicado: (2018)

Hydrogen sulfide to the rescue in obstructive kidney injury
por: Kasinath, Balakuntalam S.
Publicado: (2014)

Rhein Inhibits Autophagy in Rat Renal Tubular Cells by Regulation of AMPK/mTOR Signaling
por: Tu, Yue, et al.
Publicado: (2017)

Mesenchymal Stem Cell Protects Injured Renal Tubular Epithelial Cells by Regulating mTOR-Mediated Th17/Treg Axis
por: Luo, Yongsheng, et al.
Publicado: (2021)

Erk in Kidney Diseases
por: Feliers, Denis, et al.
Publicado: (2011)

Vitamin D receptor and epigenetics in HIV infection and drug abuse
por: Chandel, Nirupama, et al.
Publicado: (2015)

Proximal tubular epithelial insulin receptor mediates high-fat diet–induced kidney injury
por: Lee, Hak Joo, et al.
Publicado: (2021)

Revisiting mTOR and Epithelial–Mesenchymal Transition
por: Herrerias, Mariana M., et al.
Publicado: (2020)

Taurine suppresses ROS-dependent autophagy via activating Akt/mTOR signaling pathway in calcium oxalate crystals-induced renal tubular epithelial cell injury
por: Sun, Yan, et al.
Publicado: (2020)

Elevated glucose represses lysosomal and mTOR-related genes in renal epithelial cells composed of progenitor CD133(+) cells
por: Shrestha, Swojani, et al.
Publicado: (2021)

Correction for: Taurine suppresses ROS-dependent autophagy via activating Akt/mTOR signaling pathway in calcium oxalate crystals-induced renal tubular epithelial cell injury
por: Sun, Yan, et al.
Publicado: (2021)

TGFβ-Stimulated MicroRNA-21 Utilizes PTEN to Orchestrate AKT/mTORC1 Signaling for Mesangial Cell Hypertrophy and Matrix Expansion
por: Dey, Nirmalya, et al.
Publicado: (2012)

Regulation of Glomerular Endothelial Cell Proteoglycans by Glucose
por: Ha, Tae-Sun, et al.
Publicado: (2004)

Optimising the use of mTOR inhibitors in renal transplantation
por: Russ, Graeme R
Publicado: (2013)

MicroRNA-93 inhibits the apoptosis and inflammatory response of tubular epithelial cells via the PTEN/AKT/mTOR pathway in acute kidney injury
por: Zhan, Yaping, et al.
Publicado: (2021)

mTOR's role in ageing: protein synthesis or autophagy?
por: Hands, Sarah L., et al.
Publicado: (2009)

Cellular senescence of renal tubular epithelial cells in renal fibrosis
por: Zhang, Jun-Qing, et al.
Publicado: (2023)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

Role of tubular epithelial arginase-II in renal inflammaging
por: Huang, Ji, et al.
Publicado: (2021)

Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling
por: Berard, Alicia R., et al.
Publicado: (2023)

MEN1/Menin regulates milk protein synthesis through mTOR signaling in mammary epithelial cells
por: Li, Honghui, et al.
Publicado: (2017)

Fatigue characteristics on dialysis and non-dialysis days in patients with chronic kidney failure on maintenance hemodialysis
por: Debnath, Subrata, et al.
Publicado: (2021)

YB-1 Synthesis Is Regulated by mTOR Signaling Pathway
por: Lyabin, Dmitry N., et al.
Publicado: (2012)

mTOR coordinates protein synthesis, mitochondrial activity and proliferation
por: Morita, Masahiro, et al.
Publicado: (2015)

Myelination and mTOR
por: Figlia, Gianluca, et al.
Publicado: (2017)

Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma
por: Merimsky, Ofer, et al.
Publicado: (2008)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
por: Zou, Zhilin, et al.
Publicado: (2020)

POSTN promotes proliferation and epithelial-mesenchymal transition in renal cell carcinoma through ILK/AKT/mTOR pathway
por: Jia, Yuan-yuan, et al.
Publicado: (2021)

Thioredoxin interacting protein (TXNIP) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTOR signaling pathway
por: Huang, Chunling, et al.
Publicado: (2016)

AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells
por: Yoshinaga, Tomoyo, et al.
Publicado: (2016)

Acetate-Induced Milk Fat Synthesis Is Associated with Activation of the mTOR Signaling Pathway in Bovine Mammary Epithelial Cells
por: Lin, Miao, et al.
Publicado: (2022)

Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression
por: Wu, Mingsong, et al.
Publicado: (2015)

Point mutations of the mTOR-RHEB pathway in renal cell carcinoma
por: Ghosh, Arindam P., et al.
Publicado: (2015)

Vitexin suppresses renal cell carcinoma by regulating mTOR pathways
por: Li, Yuhong, et al.
Publicado: (2020)

mTOR Inhibitors Induce Erythropoietin Resistance in Renal Transplant Recipients
por: Jefferies, Reece, et al.
Publicado: (2022)

Roles of DNA damage in renal tubular epithelial cells injury
por: Wang, Peipei, et al.
Publicado: (2023)

Routes of Albumin Overload Toxicity in Renal Tubular Epithelial Cells
por: Eleftheriadis, Theodoros, et al.
Publicado: (2023)

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
por: Tian, Tian, et al.
Publicado: (2019)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
por: Tiedemann, Kerstin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_u7jsqs0u8a0l24rt9mnb04njst