TCR cross-reactivity and allorecognition: new insights into the immunogenetics of allorecognition

Alloreactive T cells are core mediators of graft rejection and are a potent barrier to transplantation tolerance. It was previously unclear how T cells educated in the recipient thymus could recognize allogeneic HLA molecules. Recently it was shown that both naïve and memory CD4(+) and CD8(+) T cell...

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Detalles Bibliográficos
Autores principales: D’Orsogna, L. J., Roelen, D. L., Doxiadis, I. I. N., Claas, F. H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253994/
https://www.ncbi.nlm.nih.gov/pubmed/22146829
http://dx.doi.org/10.1007/s00251-011-0590-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253994/
https://www.ncbi.nlm.nih.gov/pubmed/22146829
http://dx.doi.org/10.1007/s00251-011-0590-0

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