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TCR cross-reactivity and allorecognition: new insights into the immunogenetics of allorecognition
Alloreactive T cells are core mediators of graft rejection and are a potent barrier to transplantation tolerance. It was previously unclear how T cells educated in the recipient thymus could recognize allogeneic HLA molecules. Recently it was shown that both naïve and memory CD4(+) and CD8(+) T cell...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253994/ https://www.ncbi.nlm.nih.gov/pubmed/22146829 http://dx.doi.org/10.1007/s00251-011-0590-0 |