The DNA Replication Stress Hypothesis of Alzheimer's Disease

A well-recognized theory of Alzheimer's disease (AD) pathogenesis suggests ectopic cell cycle events to mediate neurodegeneration. Vulnerable neurons of the AD brain exhibit biomarkers of cell cycle progression and DNA replication suggesting a reentry into the cell cycle. Chromosome reduplicati...

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Detalles Bibliográficos
Autores principales: Yurov, Yuri B., Vorsanova, Svetlana G., Iourov, Ivan Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2012
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254013/
https://www.ncbi.nlm.nih.gov/pubmed/22262948
http://dx.doi.org/10.1100/2011/625690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254013/
https://www.ncbi.nlm.nih.gov/pubmed/22262948
http://dx.doi.org/10.1100/2011/625690

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