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The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas

BACKGROUND: The PI3K/Akt pathway is involved in cellular survival pathways by inhibiting apoptotic processes and stimulating cell growth and proliferation. Its negative prognostic value has been proven in many types of cancer. In soft tissue sarcomas, the expression profiles of the PI3K/Akt pathway...

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Detalles Bibliográficos
Autores principales: Valkov, Andrej, Kilvaer, Thomas K, Sorbye, Sveinung W, Donnem, Tom, Smeland, Eivind, Bremnes, Roy M, Busund, Lill-Tove
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254077/
https://www.ncbi.nlm.nih.gov/pubmed/22107784
http://dx.doi.org/10.1186/1479-5876-9-200