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The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas
BACKGROUND: The PI3K/Akt pathway is involved in cellular survival pathways by inhibiting apoptotic processes and stimulating cell growth and proliferation. Its negative prognostic value has been proven in many types of cancer. In soft tissue sarcomas, the expression profiles of the PI3K/Akt pathway...
Autores principales: | Valkov, Andrej, Kilvaer, Thomas K, Sorbye, Sveinung W, Donnem, Tom, Smeland, Eivind, Bremnes, Roy M, Busund, Lill-Tove |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254077/ https://www.ncbi.nlm.nih.gov/pubmed/22107784 http://dx.doi.org/10.1186/1479-5876-9-200 |
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