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Mammary tumors that become independent of the type I insulin-like growth factor receptor express elevated levels of platelet-derived growth factor receptors

BACKGROUND: Targeted therapies are becoming an essential part of breast cancer treatment and agents targeting the type I insulin-like growth factor receptor (IGF-IR) are currently being investigated in clinical trials. One of the limitations of targeted therapies is the development of resistant vari...

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Detalles Bibliográficos
Autores principales: Campbell, Craig I, Moorehead, Roger A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254084/
https://www.ncbi.nlm.nih.gov/pubmed/22070644
http://dx.doi.org/10.1186/1471-2407-11-480