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Adaptation to statins restricts human tumour growth in Nude mice

BACKGROUND: Statins have long been used as anti-hypercholesterolemia drugs, but numerous lines of evidence suggest that they may also bear anti-tumour potential. We have recently demonstrated that it was possible to isolate cancer cells adapted to growth in the continuous presence of lovastatin. The...

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Detalles Bibliográficos
Autores principales: Follet, Julie, Rémy, Lionel, Hesry, Vincent, Simon, Brigitte, Gillet, Danièle, Auvray, Pierrick, Corcos, Laurent, Le Jossic-Corcos, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254125/
https://www.ncbi.nlm.nih.gov/pubmed/22107808
http://dx.doi.org/10.1186/1471-2407-11-491