Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII

BACKGROUND: Hemophilia A is a bleeding disorder caused by deficiency in coagulation factor VIII. Recombinant factor VIII (rFVIII) is an alternative to plasma-derived FVIII for the treatment of hemophilia A. However, commercial manufacturing of rFVIII products is inefficient and costly and is associa...

Descripción completa

Detalles Bibliográficos
Autores principales: Swiech, Kamilla, Kamen, Amine, Ansorge, Sven, Durocher, Yves, Picanço-Castro, Virgínia, Russo-Carbolante, Elisa MS, Neto, Mário SA, Covas, Dimas T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254136/
https://www.ncbi.nlm.nih.gov/pubmed/22115125
http://dx.doi.org/10.1186/1472-6750-11-114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254136/
https://www.ncbi.nlm.nih.gov/pubmed/22115125
http://dx.doi.org/10.1186/1472-6750-11-114

Ejemplares similares