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Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I
BACKGROUND: The nonstructural protein 1 (NSP1) of rotavirus has been reported to block interferon (IFN) signaling by mediating proteasome-dependent degradation of IFN-regulatory factors (IRFs) and (or) the β-transducin repeat containing protein (β-TrCP). However, in addition to these targets, NSP1 m...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254192/ https://www.ncbi.nlm.nih.gov/pubmed/22152002 http://dx.doi.org/10.1186/1743-422X-8-526 |