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Mycobacterium tuberculosis RNA Expression Patterns in Sputum Bacteria Indicate Secreted Esx Factors Contributing to Growth are Highly Expressed in Active Disease

To identify factors contributing to the ability of tubercle bacilli to grow in the lung during active infection, we analyzed RNA expression patterns in bacteria present in patient sputum. Prominent among bacterial transcripts identified were those encoding secreted peptides of the Esat-6 subfamily t...

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Detalles Bibliográficos
Autores principales: Bukka, Archana, Price, Christopher T. D., Kernodle, Douglas S., Graham, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254194/
https://www.ncbi.nlm.nih.gov/pubmed/22291682
http://dx.doi.org/10.3389/fmicb.2011.00266