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Remodeling of the Natural Product Fumagillol Employing a Reaction Discovery Approach

In search for new biologically active molecules, diversity-oriented synthetic (DOS) strategies break through the limitation of traditional library synthesis by sampling new chemical space. Many natural products can be regarded as intriguing starting points for DOS, wherein stereochemically rich core...

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Detalles Bibliográficos
Autores principales: Balthaser, Bradley R., Maloney, Meghan C., Beeler, Aaron B., Porco, John A., Snyder, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254213/
https://www.ncbi.nlm.nih.gov/pubmed/22213919