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Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer

PURPOSE: The failure of cancer treatments is partly due to the enrichment of cancer stem-like cells (CSLCs) that are resistant to conventional chemotherapy. A novel micelle formulation of oxaliplatin (OXA) encapsulated in chitosan vesicle was developed. The authors postulate that micelle encapsulati...

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Detalles Bibliográficos
Autores principales: Wang, Ke, Liu, Lina, Zhang, Tao, Zhu, Yong-liang, Qiu, Fuming, Wu, Xian-guo, Wang, Xiao-lei, Hu, Fu-qiang, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254265/
https://www.ncbi.nlm.nih.gov/pubmed/22238509
http://dx.doi.org/10.2147/IJN.S26268