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Sequence Analysis of the IL28A/IL28B Inverted Gene Duplication That Contains Polymorphisms Associated with Treatment Response in Hepatitis C Patients

Several SNPs located in or around the IL28B gene are associated with response of patients infected with Hepatitis C virus to treatment with pegylated interferon-α +/− ribavirin or with spontaneous clearance of the virus. The results of such studies are so compelling that future treatment approaches...

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Detalles Bibliográficos
Autores principales: Reynolds, Jennifer M., Paciga, Sara A., Sanders, Frances A., Hyde, Craig L., Loomis, A. Katrina, Johnston, Geoffrey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254624/
https://www.ncbi.nlm.nih.gov/pubmed/22253847
http://dx.doi.org/10.1371/journal.pone.0029983