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Targeting RNA Polymerase Primary σ(70) as a Therapeutic Strategy against Methicillin-Resistant Staphylococcus aureus by Antisense Peptide Nucleic Acid

BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) causes threatening infection-related mortality worldwide. Currently, spread of multi-drug resistance (MDR) MRSA limits therapeutic options and requires new approaches to “druggable” target discovery, as well as development of novel MRSA-...

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Detalles Bibliográficos
Autores principales: Bai, Hui, Sang, Guojun, You, Yu, Xue, Xiaoyan, Zhou, Ying, Hou, Zheng, Meng, Jingru, Luo, Xiaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254626/
https://www.ncbi.nlm.nih.gov/pubmed/22253815
http://dx.doi.org/10.1371/journal.pone.0029886