Osmolarity and Glucose Differentially Regulate Aldose Reductase Activity in Cultured Mouse Podocytes

Podocyte injury is associated with progression of many renal diseases, including diabetic nephropathy. In this study we examined whether aldose reductase (AR), the enzyme implicated in diabetic complications in different tissues, is modulated by high glucose and osmolarity in podocyte cells. AR mRNA...

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Detalles Bibliográficos
Autores principales: Lewko, Barbara, Latawiec, Elżbieta, Maryn, Anna, Barczyńska, Anna, Pikuła, Michał, Zieliński, Maciej, Rybczyńska, Apolonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255165/
https://www.ncbi.nlm.nih.gov/pubmed/22253613
http://dx.doi.org/10.1155/2011/278963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255165/
https://www.ncbi.nlm.nih.gov/pubmed/22253613
http://dx.doi.org/10.1155/2011/278963

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