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Dietary Restriction Promotes Vessel Maturation in a Mouse Astrocytoma

Mature vasculature contains an endothelial cell lining with a surrounding sheath of pericytes/vascular smooth muscle cells (VSMCs). Tumor vessels are immature and lack a pericyte sheath. Colocalization of vascular endothelial growth factor receptor 2 (VEGFR-2) and platelet-derived growth factor rece...

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Detalles Bibliográficos
Autores principales: Urits, Ivan, Mukherjee, Purna, Meidenbauer, Joshua, Seyfried, Thomas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255299/
https://www.ncbi.nlm.nih.gov/pubmed/22253625
http://dx.doi.org/10.1155/2012/264039