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Synthesis and antimalarial evaluation of some 4-quinazolinone derivatives based on febrifugine

A series of 2-substituted and 2,3-substituted quinazolin -4(3H)-one derivatives were designed and synthesized based on the structure of febrifugine. The structures of the new compounds were confirmed by spectral analysis. The in vivo biological activity test results indicated that those compounds ex...

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Detalles Bibliográficos
Autores principales: Sen, Debanjan, Banerjee, Anirban, Ghosh, Ashoke Kumar, Chatterjee, Tapan Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255402/
https://www.ncbi.nlm.nih.gov/pubmed/22247880
http://dx.doi.org/10.4103/0110-5558.76439