A novel potent Fas agonist for selective depletion of tumor cells in hematopoietic transplants

There remains a clear need for effective tumor cell purging in autologous stem cell transplantation (ASCT) where residual malignant cells within the autograft contribute to disease relapse. Here we propose the use of a novel Fas agonist with potent pro-apoptotic activity, termed MegaFasL, as an effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Nahimana, A, Aubry, D, Lagopoulos, L, Greaney, P, Attinger, A, Demotz, S, Dawson, K M, Schapira, M, Tschopp, J, Dupuis, M, Duchosal, M A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255509/
https://www.ncbi.nlm.nih.gov/pubmed/22829095
http://dx.doi.org/10.1038/bcj.2011.47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255509/
https://www.ncbi.nlm.nih.gov/pubmed/22829095
http://dx.doi.org/10.1038/bcj.2011.47

Ejemplares similares