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Modeling psychiatric disorders through reprogramming

Psychiatric disorders, including autism spectrum disorders and schizophrenia, are extremely heritable complex genetic neurodevelopmental disorders. It is now possible to directly reprogram fibroblasts from psychiatric patients into human induced pluripotent stem cells (hiPSCs) and subsequently diffe...

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Detalles Bibliográficos
Autores principales: Brennand, Kristen J., Gage, Fred H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255540/
https://www.ncbi.nlm.nih.gov/pubmed/21954066
http://dx.doi.org/10.1242/dmm.008268