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Studying synthetic lethal interactions in the zebrafish system: insight into disease genes and mechanisms
The post-genomic era is marked by a pressing need to functionally characterize genes through understanding gene-gene interactions, as well as interactions between biological pathways. Exploiting a phenomenon known as synthetic lethality, in which simultaneous loss of two interacting genes leads to l...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Limited
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255541/ https://www.ncbi.nlm.nih.gov/pubmed/22107871 http://dx.doi.org/10.1242/dmm.007989 |