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An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening

Because Ras signaling is frequently activated by major hepatocellular carcinoma etiological factors, a transgenic zebrafish constitutively expressing the kras(V12) oncogene in the liver was previously generated by our laboratory. Although this model depicted and uncovered the conservation between ze...

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Detalles Bibliográficos
Autores principales: Nguyen, Anh Tuan, Emelyanov, Alexander, Koh, Chor Hui Vivien, Spitsbergen, Jan M., Parinov, Serguei, Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255544/
https://www.ncbi.nlm.nih.gov/pubmed/21903676
http://dx.doi.org/10.1242/dmm.008367