Repletion of TNFα or leptin in calorically restricted mice suppresses post-restriction hyperphagia

The causes of post-restriction hyperphagia (PRH) represent a target for drug-based therapies to prevent obesity. However, the factors causing PRH are poorly understood. We show that, in mice, the extent of PRH was independent of the time under restriction, but depended on its severity, suggesting th...

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Detalles Bibliográficos
Autores principales: Hambly, Catherine, Duncan, Jacqueline S., Archer, Zoë A., Moar, Kim M., Mercer, Julian G., Speakman, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255546/
https://www.ncbi.nlm.nih.gov/pubmed/21954068
http://dx.doi.org/10.1242/dmm.007781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255546/
https://www.ncbi.nlm.nih.gov/pubmed/21954068
http://dx.doi.org/10.1242/dmm.007781

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