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Repletion of TNFα or leptin in calorically restricted mice suppresses post-restriction hyperphagia
The causes of post-restriction hyperphagia (PRH) represent a target for drug-based therapies to prevent obesity. However, the factors causing PRH are poorly understood. We show that, in mice, the extent of PRH was independent of the time under restriction, but depended on its severity, suggesting th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Limited
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255546/ https://www.ncbi.nlm.nih.gov/pubmed/21954068 http://dx.doi.org/10.1242/dmm.007781 |