Testosterone treatment fails to accelerate disease in a transgenic mouse model of spinal and bulbar muscular atrophy

Evidence from multiple animal models demonstrates that testosterone plays a crucial role in the progression of symptoms in spinal and bulbar muscular atrophy (SBMA), a condition that results in neurodegeneration and muscle atrophy in affected men. Mice bearing a transgene encoding a human androgen r...

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Detalles Bibliográficos
Autores principales: Chevalier-Larsen, Erica S., Merry, Diane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255552/
https://www.ncbi.nlm.nih.gov/pubmed/21954065
http://dx.doi.org/10.1242/dmm.007849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255552/
https://www.ncbi.nlm.nih.gov/pubmed/21954065
http://dx.doi.org/10.1242/dmm.007849

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