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α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction
We have developed an in vitro assay to study actin assembly at cadherin-enriched cell junctions. Using this assay, we demonstrate that cadherin-enriched junctions can polymerize new actin filaments but cannot capture preexisting filaments, suggesting a mechanism involving de novo synthesis. In agree...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255975/ https://www.ncbi.nlm.nih.gov/pubmed/22232703 http://dx.doi.org/10.1083/jcb.201103116 |