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α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction

We have developed an in vitro assay to study actin assembly at cadherin-enriched cell junctions. Using this assay, we demonstrate that cadherin-enriched junctions can polymerize new actin filaments but cannot capture preexisting filaments, suggesting a mechanism involving de novo synthesis. In agree...

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Detalles Bibliográficos
Autores principales: Tang, Vivian W., Brieher, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255975/
https://www.ncbi.nlm.nih.gov/pubmed/22232703
http://dx.doi.org/10.1083/jcb.201103116

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