PAI-1–regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy

Disruption of skeletal muscle homeostasis by substitution with fibrotic tissue constitutes the principal cause of death in Duchenne muscular dystrophy (DMD) patients, yet the implicated fibrogenic mechanisms remain poorly understood. This study identifies the extracellular PAI-1/urokinase-type plasm...

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Detalles Bibliográficos
Autores principales: Ardite, Esther, Perdiguero, Eusebio, Vidal, Berta, Gutarra, Susana, Serrano, Antonio L., Muñoz-Cánoves, Pura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255978/
https://www.ncbi.nlm.nih.gov/pubmed/22213800
http://dx.doi.org/10.1083/jcb.201105013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255978/
https://www.ncbi.nlm.nih.gov/pubmed/22213800
http://dx.doi.org/10.1083/jcb.201105013

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