Replication competent HIV-1 viruses that express intragenomic microRNA reveal discrete RNA-interference mechanisms that affect viral replication

BACKGROUND: It remains unclear whether retroviruses can encode and express an intragenomic microRNA (miRNA). Some have suggested that processing by the Drosha and Dicer enzymes might preclude the viability of a replicating retroviral RNA genome that contains a cis-embedded miRNA. To date, while many...

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Detalles Bibliográficos
Autores principales: Klase, Zachary, Houzet, Laurent, Jeang, Kuan-Teh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256098/
https://www.ncbi.nlm.nih.gov/pubmed/22112720
http://dx.doi.org/10.1186/2045-3701-1-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256098/
https://www.ncbi.nlm.nih.gov/pubmed/22112720
http://dx.doi.org/10.1186/2045-3701-1-38

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