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Factor Xa Generation by Computational Modeling: An Additional Discriminator to Thrombin Generation Evaluation

Factor (f)Xa is a critical enzyme in blood coagulation that is responsible for the initiation and propagation of thrombin generation. Previously we have shown that analysis of computationally generated thrombin profiles is a tool to investigate hemostasis in various populations. In this study, we ev...

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Detalles Bibliográficos
Autores principales: Brummel-Ziedins, Kathleen E., Orfeo, Thomas, Gissel, Matthew, Mann, Kenneth G., Rosendaal, Frits R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256151/
https://www.ncbi.nlm.nih.gov/pubmed/22247769
http://dx.doi.org/10.1371/journal.pone.0029178