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Reduction of Mitoferrin Results in Abnormal Development and Extended Lifespan in Caenorhabditis elegans
Iron is essential for organisms. It is mainly utilized in mitochondria for biosynthesis of iron-sulfur clusters, hemes and other cofactors. Mitoferrin 1 and mitoferrin 2, two homologues proteins belonging to the mitochondrial solute carrier family, are required for iron delivery into mitochondria. M...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256167/ https://www.ncbi.nlm.nih.gov/pubmed/22253756 http://dx.doi.org/10.1371/journal.pone.0029666 |