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Dual Effect of Beta-Amyloid on α7 and α4β2 Nicotinic Receptors Controlling the Release of Glutamate, Aspartate and GABA in Rat Hippocampus

BACKGROUND: We previously showed that beta-amyloid (Aβ), a peptide considered as relevant to Alzheimer's Disease, is able to act as a neuromodulator affecting neurotransmitter release in absence of evident sign of neurotoxicity in two different rat brain areas. In this paper we focused on the h...

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Detalles Bibliográficos
Autores principales: Mura, Elisa, Zappettini, Stefania, Preda, Stefania, Biundo, Fabrizio, Lanni, Cristina, Grilli, Massimo, Cavallero, Anna, Olivero, Guendalina, Salamone, Alessia, Govoni, Stefano, Marchi, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256170/
https://www.ncbi.nlm.nih.gov/pubmed/22253754
http://dx.doi.org/10.1371/journal.pone.0029661